Thursday, September 29, 2011

Richard Resnick: Welcome to the genomic revolution

In this accessible talk from TEDxBoston, Richard Resnick shows how cheap and fast genome sequencing is about to turn health care (and insurance, and politics) upside down.


Ladies and gentlemen, I present to you the human genome. (Applause) Chromosome one, top left.Bottom right are the sex chromosomes. Women have two copies of that big X chromosome; men have the Xand, of course, that small copy of the Y. Sorry boys, but it's just a tiny little thing that makes you different.So if you zoom in on this genome, then what you see, of course, is this double helix structure -- the code of life spelled out with these four biochemical letters, or we call them bases, right: A, C, G and T. How many are there in the human genome? Three billion. Is that a big number? Well, everybody can throw around big numbers. But in fact, if I were to place one base on each pixel of this 1280 by 800 resolution screen, we would need 3,000 screens to take a look at the genome. So it's really quite big.
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